Non-Cardiogenic Pulmonary Edema With Refractory Hypotension in a Child From Amlodipine Overdoses

Non-Cardiogenic Pulmonary Edema

Non-Cardiogenic Pulmonary Edema

T he barrier between pulmonary capillaries and alveolar gas consists of a series of three anatomical layers with distinct structural characteristics. The cytoplasmic projections of the capillary endothelial cells represent the first layer of this barrier and overlap to form a continuous cytoplasmic tube. At the overlapping junctions of these cytoplasmic projections are clefts of varying sizes (...

Noncardiogenic Pulmonary Edema after Amlodipine Overdose without Refractory Hypotension and Bradycardia

Amlodipine overdose can be life-threatening when manifesting as noncardiogenic pulmonary edema. Treatment remains challenging. We describe a case of noncardiogenic pulmonary edema without refractory hypotension and bradycardia after ingestion of 500 milligram amlodipine with suicidal intent. Mechanical ventilation, dexamethasone, atrovent HFA (ipratropium), pulmicort inhalation, and antibiotic ...

Non-Cardiogenic Pulmonary Edema in Salicylate Posioning

Salicylate-induced pulmonary edema (SIPE) can occur in both acute and chronic users of aspirin or salicylate products. The medical history, especially when it reveals the use of salicylates, is critical when considering this diagnosis. Unfortunately, the neurologic and systemic effects of salicylate toxicity may hinder the ability to obtain a reliable medical history. SIPE should be considered ...

Hydrochlorothiazide-induced acute non-cardiogenic pulmonary edema.

We report the case of a 64 year-old male with non cardiogenic pulmonary edema episodes after oral administration of 12.5 mg of hydrochlorothiazide. In vitro immunologic study with basophil activation test and late cellular activation study (CD69 and production of interferon gamma) with chlorothiazide were performed, and no activation was observed. As a consequence, like in previous cases publis...